Claudin 14 Chicken anti-Human, Polyclonal, Invitrogen™
Chicken Polyclonal Antibody
Manufacturer: Invitrogen PA19540
PA1-9540 detects CLDN14 in human samples. PA1-9540 has been successfully used in Western blot procedures. By Western blot, PA1-9540 detects a 26 kDa protein representing CLDN14. PA1-9540 immunogen is a purified recombit CLDN14 corresponding to the chromosome 21 gene (Human).Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. Several transcript variants encoding the same protein have been found for this gene.
|Purified recombit CLDN14 corresponding to the chromosome 21 gene (Human).|
|PBS with 0.02% sodium azide|
|-20° C, Avoid Freeze/Thaw Cycles|
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