Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Lamin A (Cleaved Asp230) Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA517838

Catalog No. PIPA517838


Add to cart

Description

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with full length lamin A or lamin C.

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
Specifications

Specifications

Lamin A (Cleaved Asp230)
Polyclonal
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
P02545, P48678, P48679
70 kDa lamin; OTTHUMP00000015843; OTTHUMP00000015846; OTTHUMP00000015847; lamin A/C-like 1; lamin-A/C; prelamin-A/C; renal carcinoma antigen NY-REN-32
Rabbit
IgG
100 μL
-20°C
Primary
16905, 4000, 60374
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
LMNA
Liquid
LMNA
Synthetic peptide corresponding to amino-terminal residues surrounding Asp230 in human lamin A
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
SDS
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit