CLEC5A Mouse anti-Human, Clone: 283834, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523909
This antibody does not cross-react with recombit mouse MDL-1. Reconstitute at 0.5 mg/mL in sterile PBS.Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation . Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
|PBS with 5% trehalose and No Preservative|
|CLECSF5, MDL-1, MDL1, C-type calcium dependent, carbohydrate-recognition domain, superfamily member 5, C-type lectin domain family 5 member A, C-type lectin superfamily member 5, myeloid DAP12-associating lectin 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Western Blot|
|Mouse myeloma cell line NS0-derived recombit human MDL-1/CLEC5A Tyr26-Lys188|
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