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CNTF Chicken anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Chicken Polyclonal Antibody

Manufacturer:  Invitrogen PA19521

Catalog No. 01-674-404


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Description

Description

PA1-9521 detects CNTF in human, mouse and rat samples. PA1-9521 has been successfully used in Western blot, ELISA,and immunohistochemistry procedures. By Western blot, PA1-9521 detects a 23 kDa protein representing CNTF. PA1-9521 immunogen is a synthetic peptide based on the human CNTF protein. Store at 4°C for up to 1 week, and -20°C as undiluted liquid long-term.

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
Specifications

Specifications

CNTF
Polyclonal
Unconjugated
CNTF
Liquid
CNTF
Synthetic peptide based on the human CNTF protein.
IgY fraction
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P26441, P51642, P20294
ciliary neurotrophic factor
Chicken
IgY
500 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1270, 12803, 25707
Documents
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