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Factor VII Rat anti-Mouse, Clone: 406722, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA524143

Catalog No. PIMA524143


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Description

Description

In direct ELISAs, no cross-reactivity with recombit human (rh) FGFA, rhFactor VII, rhFactor X, rhFactor XI, rhPROC, rhThrombin, rhUPA1, rhKLK-1, -2, -3, -4, -5, -7, -8, -9, -10, -11, -12, -13, -14, -15, or -B1 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
Specifications

Specifications

Factor VII
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P70375
Coagulation factor VII, Proconvertin, Coagulation factor 7, Serum prothrombin conversion accelerator, SPCA
Rat
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
14068
Immunoprecipitation, Western Blot
406722
Unconjugated
F7
Lyophilized
F7
CHO-derived recombit mouse Coagulation Factor VII Ala42-Leu446
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Documents
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