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Collagen II Rabbit anti-Bovine, Human, Mouse, Ovine, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA126206

Catalog No. PA126206

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PA1-26206 detects Collagen II from bovine and human samples. PA1-26206 is expected to cross react with most mammals due to sequence homology. This antibody shows negligable cross reactivity with the Collagens 1, 3, 4, 5, and 6. PA1-26206 has been successfully used in ELISA, Immunohistochemistry (P), immunoprecipitation, and Western blot procedures. The PA1-26206 immunogen is Collagen type II from adult human knee cartilage and bovine nasal cartilage. Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20° C or below, avoiding multiple freeze-thaw cycles.

COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.


Collagen II
Collagen type II from adult human knee cartilage and bovine nasal cartilage.
Antigen affinity chromatography
Bovine, Human, Mouse, Ovine, Rat
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1 mg/mL
0.125M sodium borate with 5mM EDTA and 0.01% sodium azide; pH 8.0
P02459, P02458, P28481, P05539
Type II Collagen, Collagen 2
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
100196905, 1280, 12824, 25412, 407142
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