Collagen IV Mouse anti-Human, Clone: MC4-HA, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA135333
This antibody does not cross-react with Collagens I, II, III, or V. For immunohistochemistry on frozen sections, fixation with acetone for 5 minutes at -20°C is recommended. Immunohistochemistry on paraffin sections has worked, but is less effective than staining on frozen tissues. Reconstitute with 1 mL of distilled water. Store reconstituted product at 4°C.Collagen IV is a major constituent of the basement membranes along with laminins and enactins. It is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio. It can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.
|Collagen type IV.|
|ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)|
|Antibody with no preservative|
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