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DRP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112801

Catalog No. PIPA112801


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Description

Description

A suggested positive control for this product is brain tissue lysate.

Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.
Specifications

Specifications

DRP1
Polyclonal
PBS with 0.02% sodium azide
Q14194, P97427, Q62950
CRMP1
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
12933, 1400, 25415
Western Blot
Unconjugated
CRMP1
Liquid
CRMP1
Synthetic peptide corresponding to 15 residues from near the C-terminus of human CRMP1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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