Complement C3 Rabbit anti-Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA140288
PA1-40288 detects C3 from mouse samples. PA1-40288 has been successfully used in immunohistochemistry (frozen), immunohistochemistry (paraffin), immunofluorescence and Western blot applications. The antibody works well in both PBS and in TBS. The PA1-40288 imunogen is mouse C3. Positive control: Kidney, Spleen.The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha-chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes.
|Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.1% BSA and 0.02% sodium azide|
|Complement component 3|
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