Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Complement C5 Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA140289

Catalog No. 01-676-408


Add to cart

Description

Description

PA1-40289 detects C5 from mouse samples. PA1-40289 has been successfully used in Western blot and immunohistochemistry (frozen) applications. The PA1-40289 imunogen is mouse C5.

The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis.
Specifications

Specifications

Complement C5
Polyclonal
Unconjugated
Hc
Liquid
Hc
Murine C5.
Purified
RUO
Antibody
Polyclonal
Mouse
Immunohistochemistry (Frozen), Western Blot
0.1 mg/mL
PBS with 0.1% BSA and 0.02% sodium azide
P06684
Complement component 5
Rabbit
IgG
100 μg
4° C
Primary
15139
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit