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Complement Factor H Sheep anti-Canine, Equine, Feline, Guinea Pig, Human, Mouse, Rat, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA185423

Catalog No. PA185423


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Description

Description

This antibody does not react with bovine, chicken, goat, pig or rabbit. Sheep anti Human complement Factor H antibody recognizes human Factor H, a cofactor involved in the regulation of the alternative complement pathway.

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Specifications

Specifications

Complement Factor H
Polyclonal
glycine buffered saline with 0.01% benzamidine, 0.1% EACA, 1mM EDTA and 0.09% sodium azide; pH 7.4
P08603, P06909
AHUS1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS, MGC88246
Sheep
IgG
1 mL
4°C or -20°C if preferred
Primary
100051358, 100733902, 101089505, 12628, 155012, 3075, 478952
Immunodiffusion
Unconjugated
CFH
Liquid
CFH
Human 155kDa Factor H, purified from plasma
Ammonium sulfate precipitation, Ion-exchange chromatography
RUO
Antibody
Polyclonal
Canine, Equine, Feline, Guinea Pig, Human, Mouse, Rat
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