Complement Factor H Sheep anti-Canine, Equine, Feline, Guinea Pig, Human, Mouse, Rat, Polyclonal, Invitrogen
Sheep Polyclonal Antibody
Manufacturer: Invitrogen PA185423
This antibody does not react with bovine, chicken, goat, pig or rabbit. Sheep anti Human complement Factor H antibody recognizes human Factor H, a cofactor involved in the regulation of the alternative complement pathway.This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
|Complement Factor H|
|glycine buffered saline with 0.01% benzamidine, 0.1% EACA, 1mM EDTA and 0.09% sodium azide; pH 7.4|
|AHUS1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS, MGC88246|
|4°C or -20°C if preferred|
|100051358, 100733902, 101089505, 12628, 155012, 3075, 478952|
|Human 155kDa Factor H, purified from plasma|
|Ammonium sulfate precipitation, Ion-exchange chromatography|
|Canine, Equine, Feline, Guinea Pig, Human, Mouse, Rat|
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