COPS6 Mouse anti-Human, Clone: 2H5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA521211
Peptide Sequence: VMACGVTGSV SVALHPLVIL NISDHWIRMR SQEGRPVQVI GALIGKQEGR NIEVMNSFEL LSHTVEEKII IDKEYYYTKE EQFKQVFKEL EFLGWYTTGG PPDPSDIHVH KQVCEIIESP LFLKLNPMTK HTDLPVSVFE SVIDIINGEA TMLFAELTYT LATEEAERIG VDHVARMTAT GSGENSTVAE HLIAQHSAIK MLHSRVKLIL EYVKASEAGE VPFNHEILRE AYALCHCLPV LSTDKFKTDF YDQCNThe protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
|PBS with no preservative; pH 7.4|
|COP9 signalosome complex subunit 6; JAB1-containing signalosome subunit 6; Vpr-interacting protein; MOV34 homolog; CSN6, HVIP|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunohistochemistry (PFA fixed)|
|COPS6 (AAH02520, 30 a.a. ∽ 327 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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