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Cortisol Sheep anti-Chemical, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA175084

Catalog No. PIPA175084

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

PA1-75084 specifically detects Cortisol. PA1-75084 has been successfully used in ELISA applications. The PA1-75084 immunogen is Cortisol(4)-BTG.

Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
Specifications

Specifications

Cortisol
Polyclonal
Unconjugated
Liquid
Cortisol(4)-BTG
Purified
RUO
Antibody
Polyclonal
ELISA
7.91 mg/mL
PBS with 0.09% sodium azide
Sheep
IgG
1 mL
-20° C, Avoid Freeze/Thaw Cycles
Primary
Chemical
Documents
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