COX1 Mouse anti-Human, Clone: AS70, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA112234
This antibody does not cross-react with human COX2.PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
|PBS with 0.08% sodium azide|
|COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS, PTGS1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Human recombit COX1 protein.|
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