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COX1 Mouse anti-Human, Clone: AS70, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA112234

Catalog No. 01-670-942

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody does not cross-react with human COX2.

PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
Specifications

Specifications

COX1
Monoclonal
1 mg/mL
PBS with 0.08% sodium azide
P23219
COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS, PTGS1
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5742
Western Blot
AS70
Unconjugated
PTGS1
Liquid
PTGS1
Human recombit COX1 protein.
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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