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COX1, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA185118

Catalog No. PA185118

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.

Predicted to react with all mammals based on sequence homology.
Specifications

Specifications

COX1
Polyclonal
whole serum with 0.05% sodium azide
P22437, P05979, Q63921
PTGS1, PGHS-1, prostaglandin-endoperoxide synthase 1, prostaglandin G/H synthase 1
Goat
IgG
RUO
Antibody
Polyclonal
Chicken, Murine, Ovine, Rat
ELISA, Western Blot
Unconjugated
Ptgs1
Liquid
PTGS1
Native protein.
100μL
4°C or -20°C if preferred
Primary
19224, 24693, 427752, 443551
Documents
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