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COX1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528067

Catalog No. PIPA528067


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Description

Description

PA5-28067 targets COX1 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28067 immunogen is synthetic peptide corresponding to a region within amino acids 536 and 599 of Human COX1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
Specifications

Specifications

COX1
Polyclonal
Unconjugated
PTGS1
Liquid
PTGS1
Synthetic peptide corresponding to a region within amino acids 536 and 599 of Human COX1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 40% glycerol and 0.01% thimerosal; pH 7
P23219
COX1, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS, COX-1, PGH synthase 1, PHS 1, cyclooxygenase-1, prostaglandin G/H synthase 1, prostaglandin G/H synthase and cyclooxygenase, prostaglandin H2 synthase 1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5742
Documents
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