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CRACC Mouse anti-Human, Clone: 235614, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523900

Catalog No. PIMA523900


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Description

Description

In direct ELISAs, no cross-reactivity with Recombinant human NTB-AR is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.
Specifications

Specifications

CRACC
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q9NQ25
SLAMF7, CD319, CRACC, CS1, 19A24 protein, CD2 subset 1, CD2-like receptor activating cytotoxic cells, CD2-like receptor-activating cytotoxic cells, membrane protein FOAP-12, novel LY9 lymphocyte antigen 9 like protein, protein 19A
Mouse
IgG2A
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
57823
Flow Cytometry
235614
Unconjugated
SLAMF7
Lyophilized
SLAMF7
Mouse myeloma cell line NS0-derived recombit human CRACC/SLAMF7 Lys27-Ser225
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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