Please call 1-800-766-7000 to place your order or try our site again later.
CRACC Rat anti-Mouse, Clone: 520914, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA524227
In direct ELISAs, no cross-reactivity with recombit human CRACC is observed. Reconstitute at 0.5 mg/mL in sterile PBS.SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.
|PBS with 5% trehalose and No Preservative|
|SLAMF7, CD319, CRACC, CS1, 19A24 protein, CD2 subset 1, CD2-like receptor activating cytotoxic cells, CD2-like receptor-activating cytotoxic cells, membrane protein FOAP-12, novel LY9 lymphocyte antigen 9 like protein, protein 19A|
|-20° C, Avoid Freeze/Thaw Cycles|
|CHO-derived recombit mouse CRACC/SLAMF7 Ala22-Gly224|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok