Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Our pricing system is unavailable. You are viewing list price.
Please call 1-800-766-7000 to place your order or try our site again later.

CRACC Rat anti-Mouse, Clone: 520914, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA524227

Catalog No. PIMA524227



Description

Description

In direct ELISAs, no cross-reactivity with recombit human CRACC is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.
Specifications

Specifications

CRACC
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q8BHK6
SLAMF7, CD319, CRACC, CS1, 19A24 protein, CD2 subset 1, CD2-like receptor activating cytotoxic cells, CD2-like receptor-activating cytotoxic cells, membrane protein FOAP-12, novel LY9 lymphocyte antigen 9 like protein, protein 19A
Rat
IgG2A
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
75345
Flow Cytometry
520914
Unconjugated
Slamf7
Lyophilized
SLAMF7
CHO-derived recombit mouse CRACC/SLAMF7 Ala22-Gly224
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit