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CRHR2 Rabbit anti-Bovine, Canine, Chicken, Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523129

Catalog No. PIPA523129


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Description

Description

Suggested positive control: human brain lysate, human brain protein.

Principal Names: Corticotropin releasing hormone receptor 2 (CRHR2); Corticotropin releasing factor receptor 2 (CRF2R); CRF2; CRH2R; Official Gene Symbol: CRHR2 Gen Bank Accession Number: NP_001874 Gene ID: 1395 (Human) Gene Map Locus: 7p15.1 (Human) CRHR2 is a novel member of Secretin-family-GPCR proteins that functions as a functional receptor for CRF. It is expressed as 3 isoforms; alpha, beta and gamma. These isoforms primarily differ in their N-terminal sequence and tissue distribution. Apart from CRF, other ligands of CRHR2 include UcnI, UcnII and UcnIII. CRHR2 is involved in stress responses, cardiovascular function and gastric motility. Studies on CRHR2 deficient mice suggested a central anxiolytic effect of CRHR2. Northern Blot analysis detects CRHR2 expression in brain, hypothalamus, heart, GI, lung, skeletal muscle and vasculature.
Specifications

Specifications

CRHR2
Polyclonal
Unconjugated
CRHR2
Liquid
CRHR2
Synthetic peptide (98 CEPILDDKQRKYDLHYR 114) of CRHR2  protein.
Protein G
RUO
Antibody
Polyclonal
Bovine, Canine, Chicken, Human, Mouse, Rat
Western Blot
1.0 mg/mL
PBS with 0.05% sodium azide
Q13324, Q60748, P47866
CRF-RB, CRF2, CRFR2, HM-CRF, CRF2 receptor, beta isoform, CRH-R2, corticotropin-releasing factor receptor 2
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
12922, 1395, 395105, 482384, 521831, 64680
Documents
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