CRHR2 Rabbit anti-Bovine, Canine, Chicken, Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523129
Suggested positive control: human brain lysate, human brain protein.Principal Names: Corticotropin releasing hormone receptor 2 (CRHR2); Corticotropin releasing factor receptor 2 (CRF2R); CRF2; CRH2R; Official Gene Symbol: CRHR2 Gen Bank Accession Number: NP_001874 Gene ID: 1395 (Human) Gene Map Locus: 7p15.1 (Human) CRHR2 is a novel member of Secretin-family-GPCR proteins that functions as a functional receptor for CRF. It is expressed as 3 isoforms; alpha, beta and gamma. These isoforms primarily differ in their N-terminal sequence and tissue distribution. Apart from CRF, other ligands of CRHR2 include UcnI, UcnII and UcnIII. CRHR2 is involved in stress responses, cardiovascular function and gastric motility. Studies on CRHR2 deficient mice suggested a central anxiolytic effect of CRHR2. Northern Blot analysis detects CRHR2 expression in brain, hypothalamus, heart, GI, lung, skeletal muscle and vasculature.
|Synthetic peptide (98 CEPILDDKQRKYDLHYR 114) of CRHR2 protein.|
|Bovine, Canine, Chicken, Human, Mouse, Rat|
|PBS with 0.05% sodium azide|
|Q13324, Q60748, P47866|
|CRF-RB, CRF2, CRFR2, HM-CRF, CRF2 receptor, beta isoform, CRH-R2, corticotropin-releasing factor receptor 2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|12922, 1395, 395105, 482384, 521831, 64680|
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