Cripto Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA511911
DescriptionCripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling. Cell associated TDGF1 acts as a a Nodeal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.
|PBS with 0.09% sodium azide|
|Teratocarcinoma-derived growth factor 1; Epidermal growth factor-like cripto protein CR1; Cripto-1 growth factor; CRGF; CRIPTO|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 18-48 amino acids from the N-terminal region of human CRIPTO (TDGF1)|
|Antigen affinity chromatography|
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