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Cripto Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA511911

Catalog No. PIPA511911

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling. Cell associated TDGF1 acts as a a Nodeal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.
Specifications

Specifications

CRIPTO
Polyclonal
PBS with 0.09% sodium azide
P13385
Teratocarcinoma-derived growth factor 1; Epidermal growth factor-like cripto protein CR1; Cripto-1 growth factor; CRGF; CRIPTO
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
6997
Immunohistochemistry, Western Blot
Unconjugated
TDGF1
Liquid
TDGF1
KLH conjugated synthetic peptide between 18-48 amino acids from the N-terminal region of human CRIPTO (TDGF1)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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