DRP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520677
A suggested positive control is rat brain tissue lysate. PA5-20677 can be used with blocking peptide PEP-0795.Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.
|An 18 amino acid peptide from near the amino terminus of human CRMP1.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q14194, P97427, Q62950|
|CRMP-1, DPYSL1, DRP-1, DRP1, ULIP-3; dihydropyrimidinase related protein-1; dihydropyrimidinase-like 1; dihydropyrimidinase-related protein 1; unc-33-like phosphoprotein 3|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|12933, 1400, 25415|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok