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CAS Mouse anti-Human, Mouse, Rat, Clone: P5111, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA518301

Catalog No. PIMA518301



Description

Description

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq].
Specifications

Specifications

CAS
Monoclonal
1 mg/mL
PBS with no preservative
P55060, Q9ERK4
CAS, XPO2, CSE1 chromosome segregation 1-like yeast, CSE1
Mouse
IgG2b
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
110750, 1434, 362273
Western Blot
P5111
Unconjugated
CSE1L
Liquid
CSE1L
Recombit fragment corresponding to a region within amino acids 222 and 469 of CSE1L
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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