CSE1 chromosome segregation 1-like (yeast), Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant CSE1L.
Manufacturer: Abnova Corporation H00001434A01
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeqSequence: LIGLFELPEDDTIPDEEHFIDIEDTPGYQTAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQGYLQAARVTLL
|CSE1 chromosome segregation 1-like (yeast)|
|Human, Murine, Rat|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant CSE1L.|
|CSE1L (NP_001307, 872 a.a. ~ 971 a.a) partial recombinant protein with GST tag.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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