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CSH1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA524412

Catalog No. PIPA524412

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.
Specifications

Specifications

CSH1
Polyclonal
PBS with 0.09% sodium azide
P0DML2
CS-1, CSA, CSMT, PL, hCS-A, choriomammotropin, chorionic somatomammotropin A, chorionic somatomammotropin hormone, placental lactogen
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1442
Immunohistochemistry, Western Blot
Unconjugated
CSH1
Liquid
CSH1
KLH conjugated synthetic peptide between 177-204 amino acids from the C-terminal region of human CSH1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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