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CSK Goat anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA19034

Catalog No. 01-674-618


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Description

Description

This antibody is predicted to react with bovine and canine based on sequence homology.

Carboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine. Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK . This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive. The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk .Tissue specificity: Expressed in lung and macrophages.
Specifications

Specifications

Csk
Polyclonal
Unconjugated
CSK
Liquid
CSK
Peptide corresponding to the C terminus amino acids EQLEHIKTHELHL.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
P41240, P41241, P32577
CSK, c-src tyrosine kinase, MGC117393
Goat
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
12988, 1445, 315707
Documents
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