CTDSP2 Mouse anti-Human, Clone: 4F4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA520929
Peptide Sequence: MEHGSIITQA RREDALVLTK QGLVSKSSPK KPRGRNIFKA LFCCFRAQHV GQSSSSTELA AYKEEANTIA KSDLLQCLQY QFYQIPGTCL LPEVTEEDQG RICVVIDLDE TLVHSSFKPI NNADFIVPIE IEGTTHQVYV LKRPYVDEFL RRMGELFECV LFTASLAKYA DPVTDLLDRC GVFRARLFRE SCVFHQGCYV KDLSRLGRDL RKTLILDNSP ASYIFHPENA VPVQSWFDDM ADTELLNLIP IFEELSGAED VYTSLGQLRA PCTDSP2 is one of several small CTD phosphatases (SCP). It has been proposed that SCP activity is an evolutionarily conserved transcriptional regulator that acts globally to silence neuronal genes. In addition, expression of phosphatase CTDSP2 mRNA isenhanced in several cancer cell lines with amplification of the CTDSP2 and CDK4 genes, and CTDSP2 coamplifies with CDK4 in some primary sarcomas. CTDSP2 may contribute to the development of a subset of sarcomas.
|PBS with no preservative; pH 7.4|
|OS4, PSR2, SCP2, NLI-interacting factor 2, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, conserved gene amplified in osteosarcoma, nuclear LIM interactor-interacting factor 2, protein OS-4, small C-terminal domain phosphatase 2, small CTD phosphatase 2|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|CTDSP2 (AAH65920, 1 a.a. ∽ 271 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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