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CUEDC2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523277

Catalog No. PIPA523277


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Description

Description

CUEDC2 is a 287 amino acid protein belonging to the CUEDC2 family with a CUE domain. CUEDC2 is known to interact with PGR and ESR1 with the help of its CUE domain. The exact function of CUEDC2 is yet unknown, but reports suggest that it interacts with PR and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 participates in ubiquitination and subsequent proteasomal degradation of PGR and ESR1 and thus control their protein levels and plays an important role in breast cancer proliferation. Studies on CUEDC2 suggest that it acts as an adaptor protein that interacts with IKK and regulates IKK dephosphorylation by recruiting PP1.
Specifications

Specifications

CUEDC2
Polyclonal
Unconjugated
CUEDC2
Liquid
CUEDC2
Synthetic peptide (81 QKLSGQLSDARNKEN 95) of CUEDC2 protein.
Protein A
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q9H467
HOYS6, C10orf66, bA18I14.5, CUE domain-containing protein 2
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
79004
Documents
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