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Cullin 1, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA121787

Catalog No. PA121787

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Cullin 1 is a member of the family of human cullin genes (CUL 1, 2, 3, 4a, 4b, and 5) homologous to the S. cerevisiae cdc 53 gene. CUL 1 forms a complex with human p19 skp1 and F box protein p45 skp2, both of which, together with cdc 53 (known as CUL A), as three subunits form a ubiquitin ligase controlling proteolysis of G1 cell cycle regulatory proteins. The CUL 1/p19 skp1/p45 skp2complex is thought to play a role in the ubiquitination of G1 regulatory proteins.

PA1-21787 detects Cullin 1 in human and mouse samples. This antibody does not cross-react with rat Cullin 1.PA1-21787 has been successfully used in immunohistochemistry (FFPE), immunoprecipitation and Western Blot procedures. No special pretreatment is required for immunostaining of formalin-fixed paraffin-embedded tissue sections.The PA1-21787 immunogen is a synthetic peptide corresponding to residues C-D(742) G E K D T Y S Y L A(752) of human Cullin 1.
Specifications

Specifications

Cullin 1
Polyclonal
Unconjugated
CUL1
Purified
CUL1
Synthetic peptide corresponding to residues C-D(742) G E K D T Y S Y L A(752) of human Cullin 1.
Protein A
RUO
Antibody
Polyclonal
Human, Murine
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1mg/mL
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Q13616, Q9WTX6
CUL-1
Rabbit
IgG
500μL
Store at 4°C
Primary
8454
Documents
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