CX3CR1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA130760
PA1-30760 detects CX3CR1 from rat, mouse, human samples. PA1-30760 has been successfully used in Western blot applications. The PA1-30760 immunogen is: Synthetic peptide, corresponding to amino acids 175-189 of Human CX3CR 1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration an d adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.
|Synthetic peptide, corresponding to amino acids 175-189 of Human CX3CR 1.|
|Human, Mouse, Rat|
|PBS with 0.02% sodium azide; pH 7.4|
|P49238, Q9Z0D9, P35411|
|CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|13051, 1524, 171056|
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