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CXCL11 Mouse anti-Human, Clone: 87328, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523761

Catalog No. PIMA523761


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Description

Description

In ELISAs, this antibody does not cross-react with recombit human (rh) CXCL5, 7, 8, 9, or 10. In Western blots, this antibody shows less than 1% cross-reactivity with rhCXCL1, 2, 3, 5, 6, 7, IL-8/CXCL8, 9, 10, 13, CXCL12/SDF-1 alpha, CXCL12/SDF-1 beta, rmCXCL1, 2, 6, 9, 10, CXCL12/SDF-1 alpha, rmCXCL13, rrCXCL1, CXCL3/CINC-2 alpha, CXCL3/CINC-2 beta, or rpIL-8/CXCL8. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the domit ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.
Specifications

Specifications

CXCL11
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
O14625
CXCL11, H174, I-TAC, IP-9, IP9, MGC102770, SCYB11, SCYB9B, b-R1, C-X-C motif chemokine 11, Small-inducible cytokine B11, Interferon-inducible T-cell alpha chemoattractant, Interferon-gamma-inducible protein 9, Beta-R1
Mouse
IgG2a
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
6373
ELISA, Neutralization, Western Blot
87328
Unconjugated
CXCL11
Lyophilized
CXCL11
E. coli-derived recombit human CXCL11/I-TAC Phe22-Phe94
Protein A/G
RUO
Antibody
Monoclonal
Human
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