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CXCL17 Mouse anti-Human, Clone: 422208, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524157

Catalog No. PIMA524157


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Description

Description

In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombit mouse CXCL17 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

CXCL17 is a chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. In particular, CXCL17 is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs. CXCL17 plays a role in angiogenesis and possibly in the development of tumors. Further, CXCL17 acts as an anti-inflammatory in the stomach and may play a role in the innate defense against infections. CXCL17 also activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17 seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. Diseases associated with CXCL17 dysfunction include cholera.
Specifications

Specifications

CXCL17
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q6UXB2
CXCL17, DMC, VCC-1, Chemokine (C-X-C Motif) Ligand 17, C-X-C Motif Chemokine 17, Dcip1, Dendritic Cell And Monocyte Chemokine-Like Protein, DMC, UNQ473, VCC1, VCC-1, VEGF Coregulated Chemokine 1, VEGF Co-Regulated Chemokine 1
Mouse
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
284340
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
422208
Unconjugated
CXCL17
Lyophilized
CXCL17
E. coli-derived recombit human CXCL17/VCC-1 Leu24-Leu119
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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