CXCL17 Mouse anti-Human, Clone: 422208, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524157
In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombit mouse CXCL17 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.CXCL17 is a chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. In particular, CXCL17 is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs. CXCL17 plays a role in angiogenesis and possibly in the development of tumors. Further, CXCL17 acts as an anti-inflammatory in the stomach and may play a role in the innate defense against infections. CXCL17 also activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17 seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. Diseases associated with CXCL17 dysfunction include cholera.
|PBS with 5% trehalose and No Preservative|
|CXCL17, DMC, VCC-1, Chemokine (C-X-C Motif) Ligand 17, C-X-C Motif Chemokine 17, Dcip1, Dendritic Cell And Monocyte Chemokine-Like Protein, DMC, UNQ473, VCC1, VCC-1, VEGF Coregulated Chemokine 1, VEGF Co-Regulated Chemokine 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
|E. coli-derived recombit human CXCL17/VCC-1 Leu24-Leu119|
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