CXCL17 Rat anti-Mouse, Clone: 510614, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA524222
This antibody detects recombit mouse (rm) CXCL17/VCC-1 in direct ELISAs and Western blots. In direct ELISAs, 50% cross-reactivity with recombit human CXCL17 is observed/VCC-1. Reconstitute at 0.5 mg/mL in sterile PBS.CXCL17 is a chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. In particular, CXCL17 is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs. CXCL17 plays a role in angiogenesis and possibly in the development of tumors. Further, CXCL17 acts as an anti-inflammatory in the stomach and may play a role in the innate defense against infections. CXCL17 also activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17 seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. Diseases associated with CXCL17 dysfunction include cholera.
|PBS with 5% trehalose and No Preservative|
|CXCL17, DMC, VCC-1, Chemokine (C-X-C Motif) Ligand 17, C-X-C Motif Chemokine 17, Dcip1, Dendritic Cell And Monocyte Chemokine-Like Protein, DMC, UNQ473, VCC1, VCC-1, VEGF Coregulated Chemokine 1, VEGF Co-Regulated Chemokine 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|E. coli-derived recombit mouse CXCL17/VCC-1 Ser31-Leu119|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok