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PF4 Rat anti-Mouse, Clone: 140910, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523868

Catalog No. PIMA523868


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Description

Description

In ELISAs, this antibody does not cross-react or interfere recombit human (rh) CXCL/PF4, recombit mouse (rm) CXCL9/MIG, rmGM-CSF, rmCXCL11/I-TAC, rhCXCL8/IL-8, rmIL-5, or rhCXCL10/IP-10. In Western blots, no cross-reactivity was observed with rhGCP-2, rmGCP-2, rhGRO alpha, rhGRO beta, rhGRO gamma, rhMIP-1 alpha, rmMIP-1 alpha, rmMIP-1 beta, rhMIP-1 gamma, rmMIP-1 gamma, rmMIP-2, rhMIP-3 alpha, rmMIP-3 alpha, rrMIP-3 alpha, rhMIP-3 beta, or rmMIP-3 beta, Reconstitute at 0.5 mg/mL in sterile PBS.

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).
Specifications

Specifications

PF4
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q9Z126
PF-4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A, CXCL4, SCYB4
Rat
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
56744
ELISA, Western Blot
140910
Unconjugated
Pf4
Lyophilized
PF4
E. coli-derived recombit mouse CXCL4/PF4 Val30-Ser105
Protein A/G
RUO
Antibody
Monoclonal
Mouse
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