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CXCR1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527184

Catalog No. PIPA527184


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Description

Description

PA5-27184 targets CXCR1 in IF, IHC-P, and WB applications and shows reactivity with Human samples. The PA5-27184 immunogen is synthetic peptide corresponding to a region within amino acids 272 and 350 of Human CXCR1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
Specifications

Specifications

CXCR1
Polyclonal
Unconjugated
CXCR1
Liquid
CXCR1
Synthetic peptide corresponding to a region within amino acids 272 and 350 of Human CXCR1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.89 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
P25024
C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA, IL-8 Receptor alpha, IL-RA
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
3577
Documents
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