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CXCR3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA132503

Catalog No. PA132503


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Description

Description

PA1-32503 detects CXCR3 from human samples. PA1-32503 has been successfully used in immunohistochemistry (paraffin tissue) applications. The PA1-32503 immunogen is synthetic peptide, KLH conjugated. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.

Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Historically, CD183 was the third CXC chemokine receptor discovered and therefore, commonly designated as CXCR3. Binding of chemokines to CD183 induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. The CXC chemokine receptor (CXCR) 3, a G-protein-coupled 7-transmembrane receptor, is expressed at high levels on activated and memory T cells, B cells, natural killer cells, and plasmacytoid monocytes.
Specifications

Specifications

CXCR3
Polyclonal
Unconjugated
CXCR3
Liquid
CXCR3
Synthetic peptide, KLH conjugated.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 0.01% sodium azide; pH 7.4
P49682
CD182, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR, C-X-C chemokine receptor type 3, CXC-R3, CXCR-3, G protein-coupled receptor 9, IP-10 receptor, IP10 receptor, Mig receptor, chemokine C-X-C receptor 3, interferon-inducible protein 10 receptor
Rabbit
IgG
25 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
2833
Documents
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