CXCR3 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA132503
PA1-32503 detects CXCR3 from human samples. PA1-32503 has been successfully used in immunohistochemistry (paraffin tissue) applications. The PA1-32503 immunogen is synthetic peptide, KLH conjugated. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Historically, CD183 was the third CXC chemokine receptor discovered and therefore, commonly designated as CXCR3. Binding of chemokines to CD183 induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. The CXC chemokine receptor (CXCR) 3, a G-protein-coupled 7-transmembrane receptor, is expressed at high levels on activated and memory T cells, B cells, natural killer cells, and plasmacytoid monocytes.
|Synthetic peptide, KLH conjugated.|
|Antigen affinity chromatography|
|PBS with 0.01% sodium azide; pH 7.4|
|CD182, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR, C-X-C chemokine receptor type 3, CXC-R3, CXCR-3, G protein-coupled receptor 9, IP-10 receptor, IP10 receptor, Mig receptor, chemokine C-X-C receptor 3, interferon-inducible protein 10 receptor|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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