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CXCR7 Rabbit anti-Bovine, Equine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523192

Catalog No. PIPA523192


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Description

Description

CXCR7/RDC1 is a 362 amino acid CXC chemokine receptor involved in a number of pathobiologic processes, including cell growth, survival and adhesion, and tumor growth. It belongs to the G-protein coupled receptor 1 family. Though CXCR7 was previously identified as a receptor for vasoactive intestinal peptide (VIP), it is now considered as an orphan receptor in that its endogenous ligand has not been identified. It is an alternative receptor for CXCL12/SDF1 and ITAC (CXCL11) as well as acts as a co-receptor with CXCR4 for a restricted number of HIV isolates. Reports suggest that CXCR7 may act as a link between inflammation and cancer. This membrane protein is usually expressed in monocytes, basophils, and B-cells while low expression is also seen in CD4+ T-lymphocytes and natural killer cells.
Specifications

Specifications

CXCR7
Polyclonal
Unconjugated
ACKR3
Liquid
ACKR3
Synthetic peptide (106 QHNQWPMGELTC 116) of CXCR7/RDC1 protein.
Affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Equine, Human, Mouse, Non-human primate, Rat
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
1.0 mg/mL
tris glycine with 0.05% sodium azide
P25106, P56485, O89039
CMKOR1, CXC-R7, CXCR-7, GPR159, RDC-1, RDC1, C-X-C chemokine receptor type 7, G protein-coupled receptor, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, chemokine orphan receptor 1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100057501, 12778, 509585, 57007, 84348
Documents
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