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CXXC5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521080

Catalog No. PIPA521080


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Description

Description

A suggested positive control is human brain tissue lysate. PA5-21080 can be used with blocking peptide PEP-1194.

CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.
Specifications

Specifications

CXXC5
Polyclonal
Unconjugated
CXXC5
Liquid
CXXC5
A 15 amino acid peptide near the amino terminus of human CXXC5.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q7LFL8, Q91WA4, Q5XIQ3
HSPC195, CF5, RINF, WID; CXXC finger 5 protein; CXXC-type zinc finger protein 5; WT1-induced Inhibitor of Dishevelled; putative MAPK-activating protein PM08; putative NF-kappa-B-activating protein 102; retinoid-inducible nuclear factor
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
291670, 51523, 67393
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