Cyclophilin A Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528089
PA5-28089 targets Cyclophilin A in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-28089 immunogen is synthetic peptide corresponding to a region within amino acids 93 and 165 of Human Cyclophilin A. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.
|Synthetic peptide corresponding to a region within amino acids 93 and 165 of Human Cyclophilin A|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7|
|CYPA, CYPH, PPIase A, T cell cyclophilin, cyclophilin, cyclosporin A-binding protein, peptidyl-prolyl cis-trans isomerase A, rotamase A|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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