CYP2C19 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA525906
DescriptionCYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.
|PBS with 0.09% sodium azide|
|CPCJ, CYP2C, P450C2C, P450IIC19, (R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, CYPIIC17, CYPIIC19, S-mephenytoin 4-hydroxylase, cytochrome P-450 II C, cytochrome P450 2C19, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19, cyto|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|KLH conjugated synthetic peptide between 82-108 amino acids from the N-terminal region of human CYP2C19|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
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