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CYP2C19 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA525906

Catalog No. PIPA525906


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Description

Description

CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.
Specifications

Specifications

CYP2C19
Polyclonal
PBS with 0.09% sodium azide
P33261
CPCJ, CYP2C, P450C2C, P450IIC19, (R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, CYPIIC17, CYPIIC19, S-mephenytoin 4-hydroxylase, cytochrome P-450 II C, cytochrome P450 2C19, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19, cyto
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1557
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CYP2C19
Liquid
CYP2C19
KLH conjugated synthetic peptide between 82-108 amino acids from the N-terminal region of human CYP2C19
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
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