CYP3A7 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527976
PA5-27976 targets CYP3A7 in WB applications and shows reactivity with Human samples. The PA5-27976 immunogen is recombit fragment corresponding to a region within amino acids 222 and 489 of Human CYP3A7. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregcy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.
|Recombit fragment corresponding to a region within amino acids 222 and 489 of Human CYP3A7|
|Antigen affinity chromatography|
|0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7|
|CP37, CYPIIIA7, P450-HFLA, aryl hydrocarbon hydroxylase, cytochrome P450 3A7, cytochrome P450, subfamily IIIA, polypeptide 7, cytochrome P450-HFLA, flavoprotein-linked monooxygenase, microsomal monooxygenase, xenobiotic monooxygenase|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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