Cyp46a1 Rabbit anti-Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528207
PA5-28208 targets Cell cycle-related kinase3 in WB applications and shows reactivity with Human samples. The PA5-28208 immunogen is recombit fragment corresponding to a region within amino acids 7 and 319 of Human Cell cycle-related kinase3.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
|Recombit fragment corresponding to a region within amino acids 63 and 371 of Human CYP46A1|
|Antigen affinity chromatography|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|CP46, CYP46, CH24H, cholesterol 24-hydroxylase, cytochrome P450 46A1, cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)|
|-20° C, Avoid Freeze/Thaw Cycles|
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