CYSLTR1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528735
PA5-28735 targets CysLT 1 receptor in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28735 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CysLT 1 receptor. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
|Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CysLT 1 receptor|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, G-protein coupled receptor HG55, LTD4 receptor, cysteinyl leukotriene D4 receptor|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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