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CYSLTR1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528735

Catalog No. PIPA528735


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Description

Description

PA5-28735 targets CysLT 1 receptor in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28735 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CysLT 1 receptor. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
Specifications

Specifications

CYSLTR1
Polyclonal
Unconjugated
CYSLTR1
Liquid
CYSLTR1
Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human CysLT 1 receptor
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
0.7 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q9Y271
CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, G-protein coupled receptor HG55, LTD4 receptor, cysteinyl leukotriene D4 receptor
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
10800
Documents
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