CYSLTR1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA132500
PA1-32500 detects CysLT1 from human samples. PA1-32500 has been successfully used in immunohistochemistry (paraffin tissue) applications. The PA1-32500 immunogen is: Synthetic peptide, KLH conjugated. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
|Synthetic peptide, KLH conjugated.|
|Antigen affinity chromatography|
|PBS with 0.01% sodium azide; pH 7.7|
|CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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