Cytohesin 3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526677
This antibody is predicted to react with rat based on sequence homology.This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1.
|PBS with 0.09% sodium azide|
|ARNO3, GRP1, PSCD3, ARF nucleotide-binding site opener 3, PH, SEC7 and coiled-coil domain-containing protein 3, cytohesin-3, general receptor of phosphoinositides 1, pleckstrin homology, Sec7 and coiled-coil domains 3|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 371-400 amino acids from the C-terminal region of human CYTH3|
|Antigen affinity chromatography|
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