Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CYP3A5 Mouse anti-Bovine, Human, Clone: F18 P3 B6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA3033

Catalog No. 01-670-130


Add to cart

Description

Description

This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene.

MA3-033 detects Cytochrome P450 3A5 from HEK293 and HepG2 human cell lines, and from bovine liver and pancreas samples.MA3-033 has been successfully used in Western blot applications. By Western blot, this antibody detects a ~54kDa band representing Cytochrome P450 3A5.The MA3-033 immunogen is a synthetic peptide corresponding to residues E S R D G T L S G E, conjugated to ovalbumin.
Specifications

Specifications

CYP3A5
Monoclonal
Unconjugated
CYP3A5
Liquid
CYP3A5
Synthetic peptide corresponding to residues E S R D G T L S G E, conjugated to ovalbumin.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1577, 282214
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
F18 P3 B6
ascites with 0.05% sodium azide
P20815
CP35, P450PCN3, PCN3
Mouse
IgG1
RUO
Antibody
Monoclonal
Bovine, Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit