CYP3A7 Mouse anti-Bovine, Human, Clone: F19 P2 H2, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA3034
MA3-034 detects Cytochrome P450 3A7 from Human samples and bovine liver samples. MA3-034 has been successfully used in Western blot and Immunohistochemistry (paraffin) applications. By Western blot, this antibody detects a ∽54 kDa band representing Cytochrome P450 3A7. The MA3-034 immunogen is a synthetic peptide corresponding to residues E S R D E T V S G A, conjugated to ovalbumin.This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregcy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.
|Synthetic peptide corresponding to residues E S R D E T V S G A, conjugated to ovalbumin.|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|F19 P2 H2|
|ascites with 0.05% sodium azide|
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