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CYP3A7 Mouse anti-Bovine, Human, Clone: F19 P2 H2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA3034

Catalog No. 01-670-131


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Description

Description

MA3-034 detects Cytochrome P450 3A7 from Human samples and bovine liver samples. MA3-034 has been successfully used in Western blot and Immunohistochemistry (paraffin) applications. By Western blot, this antibody detects a ~54 kDa band representing Cytochrome P450 3A7. The MA3-034 immunogen is a synthetic peptide corresponding to residues E S R D E T V S G A, conjugated to ovalbumin.

This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregcy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.
Specifications

Specifications

CYP3A7
Monoclonal
Unconjugated
CYP3A7
Liquid
CYP3A7
Synthetic peptide corresponding to residues E S R D E T V S G A, conjugated to ovalbumin.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1551
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
F19 P2 H2
ascites with 0.05% sodium azide
P24462
CP37, P450-HFLA
Mouse
IgG1
RUO
Antibody
Monoclonal
Bovine, Human
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