Cytokeratin 14 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528002
PA5-28002 targets Cytokeratin 14 in IF, IHC (P), and WB applications and shows reactivity with Human, rat, and mouse samples. The PA5-28002 immunogen is recombit fragment corresponding to a region within amino acids 112 and 472 of Human Cytokeratin 14. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
|Recombit fragment corresponding to a region within amino acids 112 and 472 of Human Cytokeratin 14|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7|
|P02533, Q61781, Q6IFV1|
|CK14, EBS3, EBS4, K14, NFJ, CK-14, cytokeratin 14, cytokeratin-14, keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner), keratin, type I cytoskeletal 14, keratin-14|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|16664, 287701, 3861|
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