Cytokeratin 5/8 Mouse anti-Human, Clone: C50, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA112591
DescriptionCytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between ∽40 kDa and ∽68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial maligcies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
|Cytoskeleton preparation of HeLa Cells.|
|Immunohistochemistry (Frozen), Western Blot|
|PBS with 0.08% sodium azide|
|Keratin type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, CK-5, Keratin-5, K5, Type-II keratin Kb5, KRT5, Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8, KRT8, CYK8|
|-20° C, Avoid Freeze/Thaw Cycles|
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