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DAAM2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523201

Catalog No. PIPA523201


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Description

Description

DAAM2 is a recently identified planar cell polarity (PCP) signaling molecule implicated in the regulation of cellular polarity, convergent extension, and invasion. DAAM2 belongs to the formin homology family and contains a DAD (diaphanous autoregulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/ formin homology 3) domain. The DAAM2 protein is known to be involved in cell divison. Though the exact function of DAAM2 is yet unknown, reports suggest that it is closely related to DAAM1 and hence along with DAAM1 it may also be required in Wnt/Fz signaling and activation of Rho and in regulating cytoskeleton architecture. DAAM2 is expressed in most of tissues but the expression level is higher in brain.
Specifications

Specifications

DAAM2
Polyclonal
Unconjugated
DAAM2
Liquid
DAAM2
Synthetic peptide (116 YAFDEEETEMRNQVVED 132) of DAAM2 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q86T65, Q80U19
RP1-278E11.1, dJ90A20A.1, disheveled-associated activator of morphogenesis 2, dishevelled-associated activator of morphogenesis 2
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
23500, 316201, 76441
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