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DAB1 Sheep anti-Mouse, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA112426

Catalog No. 01-674-143


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Description

Description

A suggested positive control for this product is 293 cells transfected with Dab-1 HA tag.

Disruption of Dab1 results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein-protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. DAB1 acts downstream of reelin in a signalling pathway.
Specifications

Specifications

Dab1
Polyclonal
PBS with 0.08% sodium azide
P97318
RP23-356E21.1, AI956902, C630028C02Rik, scm, scr, scrambler, yot
Sheep
IgG
250 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
13131
Immunoprecipitation, Western Blot
Unconjugated
Dab1
Liquid
DAB1
residues 399-555 of mouse disabled GST fusion protein.
Ammonium sulfate precipitation
RUO
Antibody
Polyclonal
Mouse
Documents
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